中文名
重组蛋白IL-17A Protein, Mouse, Tag free, CHO
英文名
IL-17A Protein, Mouse, Tag free, CHO
描述
IL-17A 是一种同型二聚体细胞因子，在宿主防御机制中对许多细菌和真菌病原体以及过敏和自身免疫反应起着关键作用。IL-17A 诱导抗菌肽、细胞因子、趋化因子和基质金属蛋白酶的产生。
氨基酸序列
AAIIPQSSAC PNTEAKDFLQ NVKVNLKVFN SLGAKVSSRR PSDYLNRSTS PWTLHRNEDP
DRYPSVIWEA QCRHQRCVNA EGKLDHHMNS VLIQQEILVL KREPESCPFT FRVEKMLVGV
GCTCVASIVR QAA
分子量
The protein has a predicted MW of 14.97 kDa. It migrates to 15-19 kDa band in SDS-PAGE under reducing conditions due to the glycosylation.
内毒素含量
<0.2 EU per 1 µg of the protein by the LAL method.
活性
Measured by its ability to induce IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 1.1-15.5 ng/mL.
组分
Lyophilized from sterile PBS, pH 7.4, 7% trehalose.
复溶方法
Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
储存
Stored at -20 to -80°C for 12 months as supplied from date of receipt; 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid repeated freeze-thaw cycles.
关键词
rMuIL-17A;CTLA-8;IL-17A
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