中文名
重组蛋白IL-17A, Human, C-His, HEK293
英文名
IL-17A, Human, C-His, HEK293
描述
IL-17A 是一种同型二聚体细胞因子，在宿主防御机制中对许多细菌和真菌病原体以及过敏和自身免疫反应起着关键作用。IL-17A 诱导抗菌肽、细胞因子、趋化因子和基质金属蛋白酶的产生。
氨基酸序列
GITIPRNPGC PNSEDKNFPR TVMVNLNIHN RNTNTNPKRS SDYYNRSTSP WNLHRNEDPE
RYPSVIWEAK CRHLGCINAD GNVDYHMNSV PIQQEILVLR REPPHCPNSF RLEKILVSVG
CTCVTPIVHH VA
分子量
The protein has a predicted MW of 15.12 kDa. It migrates to 16-24 kDa band in SDS-PAGE under reducing conditions due to the glycosylation.
内毒素含量
<1.0 EU per 1 µg of the protein by the LAL method.
活性
Measured by its ability to induce IL-6 secretion by NIH‑3T3 cells. The ED50 for this effect is 1-10 ng/mL.
组分
Lyophilized from sterile PBS, pH 7.4, 7% trehalose.
复溶方法
Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
储存
Stored at -20 to -80°C for 12 months as supplied from date of receipt；2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid repeated freeze-thaw cycles.
关键词
Interleukin-17A;IL-17;IL-17A;Cytotoxic T-Lymphocyte-Associated Antigen 8;CTLA-8;IL17A;CTLA8;IL17
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