钯催化不对称偶联体系 手性 C-C 键构建核心试剂
2026-10-12 · 推荐产品 · 百灵威授权转载
在现代手性合成领域，不对称偶联反应是构建手性 C-C、C-N、C-O 键的核心技术，广泛应用于手性药物中间体、天然产物、功能有机材料及农用化学品的研发与生产。钯催化体系凭借底物适配范围广、反应条件温和、催化活性高、立体选择性易调控等优势，已成为不对称 Suzuki-Miyaura、Heck、Tsuji-Trost、C-H 键活化偶联等反应的主流解决方案。
为助力客户快速搭建高效、稳定的不对称偶联反应平台，我们精心遴选多种高品质钯催化剂前体与经典手性配体，重磅推出钯催化不对称偶联体系核心试剂组合。套装覆盖 0 价、+2 价等多种价态，以及不同配位环境的钯源，搭配 BINAP 系列、手性 PHOX、手性双膦等多骨架手性配体，可灵活匹配不同底物与反应类型的立体选择性需求。全系列产品纯度优异、批次稳定性强，可直接用于实验室条件筛选、工艺优化及规模化生产，一站式满足偶联反应核心试剂需求，大幅减少试剂筛选成本，加速手性化合物研发与产业化进程。
钯催化剂前体
| 品名 | CAS | 货号 |
|---|---|---|
| Palladium(II) acetate, min. 98% (99.9+%-Pd) 醋酸钯(II) | 3375-31-3 | 46-1780促 |
| Palladium(II) chloride, 99.9%, 59.8% Pd 氯化钯(II) | 7647-10-1 | 257707 |
| Tris(dibenzylideneacetone)dipalladium(0), 98%, ≥22.7% (as Pd) 三(二亚苄基丙酮)二钯(0) | 51364-51-3 | 963490 |
| Tetrakis(triphenylphosphine)palladium(0), 99% (99.9+%-Pd) 四(三苯基膦)钯 | 14221-01-3 | 46-2150 |
| Bis(dibenzylideneacetone)palladium, 98% 双(二亚苄基丙酮)钯(0) | 32005-36-0 | 141541 |
| Bis(acetylacetonato)palladium(II), 99% 双(乙酰丙酮)钯(II) | 14024-61-4 | 479131 |
| Tetrakis(acetonitrile)palladium(II) tetrafluoroborate, min. 98% 四(乙腈)四氟硼酸钯(II) | 21797-13-7 | 46-2145 |
| Allylpalladium(II) chloride dimer, 98% 氯化烯丙基钯(II)二聚物 | 12012-95-2 | 982398 |
| Palladium(II) trifluoroacetate, 32% Pd 三氟乙酸钯(II) | 42196-31-6 | 450751 |
| Sodium tetrachloropalladate(II), 99.9%, 36% Pd 四氯钯酸(II)钠 | 13820-53-6 | 132187 |
| Palladium(II) bromide, 99% 溴化钯 | 13444-94-5 | 373191 |
| Palladium(II) nitrate hydrate (Pd ~40%) (99.9%-Pd) 硝酸钯水合物 | 207596-32-5 | 93-4608 |
| Tris(dibenzylideneacetone)dipalladium(0)-chloroform adduct, 98% 三(二亚苄基丙酮)二钯(0)-氯仿加合物 | 52522-40-4 | 357699 |
| Dichlorobis(benzonitrile)palladium(II), 98% 双(苄腈)二氯化钯(II) | 14220-64-5 | 411434 |
| Dichloro(1,5-cyclooctadiene)palladium(II), 99% (1,5-环辛二烯)二氯化钯(II) | 12107-56-1 | 607604 |
手性配体
| 品名 | CAS | 货号 |
|---|---|---|
| 2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl, 98% 2,2'-双(二苯基膦基)-1,1'-联萘 | 98327-87-8 | 252679 |
| (S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl, 98% (S)-(-)-2,2'-双(二苯基膦)-1,1'-联萘 | 76189-56-5 | 137724 |
| (R)-(+)-BINAP (R)-(+)-BINAP | 76189-55-4 | B1406 |
| (R)-4-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-2-oxazoline, 98%, ee: 99% (R)-4-叔丁基-2-[2-(二苯基膦基)苯基]-2-噁唑啉 | 164858-79-1 | 1438790 |
| (S)-(-)-2-[2-(Diphenylphosphino)phenyl]-4-isopropyl-2-oxazoline, 97% (S)-(-)-2-[2-二苯基膦]苯基]-4-异丙基-2-噁唑啉 | 148461-14-7 | 177081 |
| (S,S)-(+)-2,3-Bis(t-butylmethylphosphino)quinoxaline, min. 98% (S,S)-QuinoxP* (S,S)-2,3-双(叔丁基甲基膦基)喹喔啉 | 1107608-80-9 | 15-0127 |
| (S)-(-)-5,5'-Bis[di(3,5-xylyl)phosphino]-4,4'-bi-1,3-benzodioxole, min. 98% (S)-(-)-DM-SEGPHOS （S)-(-)- 5,5-双[二（3,5 -二甲苯基）膦基]-4,4- 二-1 ,3-苯并二氧杂环戊烯 | 210169-57-6 | 15-0479促 |
| 2,6-Bis[(4R)-(+)-isopropyl-2-oxazolin-2-yl]pyridine, 98% 2,6-双[(4R)-(+)-异丙基-2-噁唑啉-2-基]吡啶 | 131864-67-0 | 353382 |
| (R)-(+)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis(diphenylphosphine), 98% (R)-(+)-(6,6'-二甲氧基联苯-2,2'-基)双(二苯基膦) | 133545-16-1 | 624280 |
| (R,R)-DACH-pyridyl Trost ligand, 97%, ee: 98% (R,R)-DACH-吡啶基 Trost 配体 | 218290-24-5 | 310494 |
| (1R,2R)-(+)-1,2-Diaminocyclohexane-N,N'-bis(2'-diphenylphosphinobenzoyl), 98% (R,R)-DACH-Phenyl Trost Ligand (1R,2R)-(+)-1,2-二胺基环己基-N,N'-双（2'-二苯基磷基苯甲酰） | 138517-61-0 | 15-0960 |
| (1S,2S)-N,N'-1,2-Diaminocyclohexanediylbis(2-pyridinecarboxamide), 97%, ee: 98% (1S,2S)-N,N'-双(2-吡啶甲酰) -1,2-环己二胺 | 172138-95-3 | 125413 |
| [S(R)]-N-[(S)-[[2-(Dicyclohexylphosphino)phenyl]phenylmethyl]-N,2-dimethyl-2-propanesulfinamide, 95% [S(R)]-N-[(S)-[[2-(二环己基膦)苯基]苯甲基]-N-甲基-2-叔丁基亚磺酰胺 | 2241598-32-1 | 9025974 |
| [S(R)]-N-[(S)-[[2-(Diphenylphosphino)phenyl]phenylmethyl]-2-methyl-2-propanesulfinamide, 95% [S(R)]-N-[(S)-[[2-(二苯基膦)苯基]苯基甲基]-2-叔丁基亚磺酰胺 | 1595319-97-3 | 9025778 |
| [S(R)]-N-((R)-(2-(Diphenylphosphanyl) phenyl)(phenyl)methyl)-2-methylpropane-2-sulfinamide, 95% [S(R)]-N-[(R)-[[2-(二苯基膦)苯基]苯基甲基]-2-叔丁基亚磺酰胺 | 1616688-59-5 | 9025779 |
| [S(R)]-N-[(1S)-2-(Diphenylphosphino)-1-[[2-(diphenylphosphino)phenyl]ethyl]-2-methyl-2-propanesulfinamide, 95% [S(R)]-N-[(1S)-2-(二苯基膦)-1-[[2-(二苯基膦)苯基]乙基]-2-叔丁基亚磺酰胺 | 1824731-39-6 | 9184522 |
| [S(R)]-N-[(S)-(Phenyl)[[5-(diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl](phenyl)methyl]-2-methyl-2-propanesulfinamide, 95% [S(R)]-N-[(S)-(苯基)[[5-(二苯基膦)-9,9-二甲基-9H-氧杂蒽]苯基甲基]-2-叔丁基亚磺酰胺 | 2162939-87-7 | 9223393 |
| [S(R)]-N-[(S)-[[2-(Diadamantanphosphino)phenyl]phenylmethyl]-2-methyl-2-propanesulfinamide, 95% [S(R)]-N-[(S)-[[2-(二金刚烷基膦)苯基]苯甲基]-2-叔丁基亚磺酰胺 | 1929530-55-1 | 9223891 |
相关产品
超干溶剂
| 品名 | CAS | 货号 |
|---|---|---|
| Tetrahydrofuran, 99.9%, SuperDry, stabilized with 250 ppm BHT, Water≤50 ppm, J&KSeal 四氢呋喃 | 109-99-9 | 315353促 危化品 |
| Acetonitrile, 99.9%, SuperDry, with molecular sieves, water≤50 ppm, J&KSeal 乙腈 | 75-05-8 | 939631促 危化品 |
| 1,2-Dichloroethane, 99.5%, SuperDry, water≤30 ppm, J&Kseal 1,2-二氯乙烷 | 107-06-2 | 991050促 危化品 |
| 1,4-Dioxane, 99.5%, SuperDry, with molecular sieves, stabilized with BHT, J&Kseal, water≤50 ppm 1,4-二氧六环 | 123-91-1 | 972869促 危化品 |
核磁检测试剂
| 品名 | CAS | 货号 |
|---|---|---|
| Dimethyl sulfoxide-d6, 99.8 atom%D, contains 0.03% v/v TMS 氘代二甲基亚砜-d6 | 2206-27-1 | 182473促 |
| Chloroform-d, 99.8 atom%D, contains 0.03% v/v TMS, packed in 10*0.6 ml ampoules 氘代氯仿 | 865-49-6 | 240987促 |
| Tetrahydrofuran-d8, 99.5 atom%D 氘代四氢呋喃-d8 | 1693-74-9 | 247731 |
| Acetonitrile-d3, 99.8 atom%D 氘代乙腈-d3 | 2206-26-0 | 236920促 |
| Dichloromethane-d2, 99.8 atom%D 氘代二氯甲烷 | 1665-00-5 | 334919促 |
| Methanol-d4, 99.8 atom%D 氘代甲醇-d4 | 811-98-3 | 114655促 |
耗材
| 品名 | CAS | 货号 |
|---|---|---|
| TLC silica gel plate (fluorescent indicator), GF254, layer thickness 0.2-0.25 mm, 100*100 mm, 80 pcs/pack 薄层色谱硅胶板(含荧光) | / | 983347 |
| Silica, powder, 200 mesh 硅胶 | 112945-52-5 | 227600 |
| Spotting capillary tube, I.D.:0.3mm, Length:100mm, 1000pcs/pack 玻璃点样毛细管 | / | 2734477 |
| 5 mm NMR Economy Sample Tube w/ Cap, 7″, High-Throughput 5毫米，高通量经济型核磁管，7英寸 | / | 1001281 |
| Digital stainless steel hotplate magnetic stirrer, with heating, heating temperature range: RT 340℃, power 550 W 数显不锈钢加热磁力搅拌器 | / | 1122416 |
| Magnetic stir bar, PTFE-coated, egg-shaped, A100 (6*10mm), 5 pcs/pack 聚四氟乙烯磁力搅拌子,椭圆型 | / | 1482821 |
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