芳香族含氟砌块——赋能分子创新，定义性能巅峰
2025-11-20 · 系列介绍 · 百灵威授权转载
在创新分子设计的舞台上，一个微小的改变往往能引发性能的飞跃。当强大的氟原子与结构多样的芳香环相遇，便诞生了驱动医药、材料等领域变革的核心引擎——芳香族含氟砌块。
百灵威致力于为您提供品类丰富、高质量的芳香族含氟砌块。我们不仅是供应商，更是您值得信赖的创新伙伴，助您精准优化分子结构，打造更具竞争力的下一代产品。
为何选择芳香族含氟砌块？——精准修饰，效能的“点睛之笔”
将三氟甲基（-CF₃）、氟原子（-F）、含氟烷氧基（-OCF₃）等基团精准引入芳香环体系，能对分子性质产生深远而积极的影响：
·“代谢稳定锚”：C-F键极高的稳定性，能有效保护芳香环免受生物体内代谢酶的攻击，显著延长药物半衰期，提升药效。
·“脂溶调节器”：含氟基团的强疏水效应能精细调节分子的脂水分配系数，优化其细胞膜穿透性与生物利用度。
·“电子效应大师”： 氟原子强大的吸电子效应，可精确调控芳香环的电子云密度，从而影响分子的酸性、碱性、偶极矩以及与生物靶点的结合强度和选择性。
·“空间位阻巧匠”： 三氟甲基等基团具有独特的立体体积，能通过空间位阻效应改变分子的构象或阻断不利的代谢位点，提高选择性并减少副作用。
产品列表：
| 品名 | CAS | 货号 |
|---|---|---|
| Fluorobenzene, 99% 氟苯 | 462-06-6 | 514999 危化品 |
| 4'-Bromo-2,2,2-trifluoroacetophenone, 97% 4'-溴-2,2,2-三氟苯乙酮 | 16184-89-7 | 211533 |
| Benzotrifluoride, 99% 三氟甲苯 | 98-08-8 | 144362 危化品 |
| Tris(pentafluorophenyl)borane, 97%, reagent grade 三(五氟苯基)硼 | 1109-15-5 | 921653 |
| 2,2'-Bis(trifluoromethyl)benzidine, 98% 2,2'-双(三氟甲基)二氨基联苯 | 341-58-2 | 126674 |
| 2,3,5,6-Tetrafluoro-4-methylbenzoic acid, 98% 2,3,5,6-四氟-4-甲基苯甲酸 | 652-32-4 | 409396 |
| 4-Fluoroaniline, 99% 4-氟苯胺 | 371-40-4 | 168767 危化品 |
| 1,4-Difluorobenzene, 99% 1,4-二氟苯 | 540-36-3 | 198235 危化品 |
| 1-(2-Fluorophenyl)piperazine, 98% 1-(2-氟苯基)哌嗪 | 1011-15-0 | 228512 |
| 4-Nitrobenzotrifluoride, 96% 4-硝基三氟甲基苯 | 402-54-0 | 421032 |
| α-Bromo-2,3,4,5,6-pentafluorotoluene, 98% α-溴-2,3,4,5,6-五氟甲苯 | 1765-40-8 | 278435 |
| (Trifluoromethoxy)benzene, 99% 三氟甲氧基苯 | 456-55-3 | 237816 |
| 2-Ethoxy-2,4,4,6,6-pentafluoro-1,3,5,2,4,6-triazatriphosphorine, 99% 乙氧基(五氟)环三磷腈 | 33027-66-6 | 1862412新 |
| 1-[4-(Trifluoromethyl)phenyl]piperazine, 97% 1-[4-(三氟甲基)苯基]哌嗪 | 30459-17-7 | 101574 |
| 2-Fluorobiphenyl, 98% 2-氟联苯 | 321-60-8 | 398815 |
| 1,3-Difluorobenzene, 99% 1,3-二氟苯 | 372-18-9 | 419889 危化品 |
| 3-Bromophenyl sulfur pentafluoride, 95% 3-溴苯基五氟化硫 | 672-30-0 | 600432 |
| 3-Bromophenyl sulfur pentafluoride, 95% 3-溴苯基五氟化硫 | 672-30-0 | 600432 |
| 3,4,5-Trifluorobenzaldehyde, 98% 3,4,5-三氟苯甲醛 | 132123-54-7 | 210057 |
| 4,4'-(Hexafluoroisopropylidene)diphthalic anhydride, 98%, for synthesis 4,4'-(六氟亚异丙基)邻苯二甲酸酐 | 1107-00-2 | 358137 |
| 2,2-Bis(4-hydroxyphenyl)hexafluoropropane, 99% 2,2-双(4-羟基苯基)六氟丙烷 | 1478-61-1 | 533153 |
| Fluorene, 98% 芴 | 86-73-7 | 334723 |
| Tris(pentafluorophenyl)borane, 97% 三(五氟苯基)硼 | 1109-15-5 | 116849 |
| 4-Fluorobenzaldehyde, 99% 4-氟苯甲醛 | 459-57-4 | 209533 |
| 1-Bromo-4-fluorobenzene, 99% 1-溴-4-氟苯 | 460-00-4 | 187086 |
| 4-(Trifluoromethyl)benzaldehyde, 98%, for synthesis 4-(三氟甲基)苯甲醛 | 455-19-6 | 495543 |
| 4-Aminobenzotrifluoride, 99% 4-氨基三氟甲基苯 | 455-14-1 | 166194 |
| 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, 99% 4-(2-氨乙基)苯磺酰氟盐酸盐 | 30827-99-7 | 554252 |
| 3,5-Bis(trifluoromethyl)phenyl isocyanate, 98%, for synthesis 3,5-双(三氟甲基)苯基异氰酸酯 | 16588-74-2 | 965709 |
| 4-Fluorobenzylamine, 99% 4-氟苄胺 | 140-75-0 | 137159 |
| α-Toluenesulfonyl fluoride, 99% α-甲苯基磺酰氟 | 329-98-6 | 562981 |
| Pentafluorophenol, 99% 五氟苯酚 | 771-61-9 | 145125 |
| Octafluorotoluene, 98% 八氟甲苯 | 434-64-0 | 580329 |
| Octafluorotoluene, 98% 八氟甲苯 | 434-64-0 | 580329 |
| Benzotrifluoride, 99%, for synthesis 三氟甲苯 | 98-08-8 | 970954 危化品 |
| 4-(Trifluoromethoxy)aniline, 99% 4-(三氟甲氧基)苯胺 | 461-82-5 | 388805 |
| Tetrafluoroterephthalonitrile, 99% 四氟对苯二甲腈 | 1835-49-0 | 963510 |
| 2-Fluorobenzoic acid, 98% 2-氟苯甲酸 | 445-29-4 | 286834 |
| 4-Fluoroaniline, 99%, for synthesis 4-氟苯胺 | 371-40-4 | 155047 危化品 |
| 4-(Trifluoromethyl)benzenesulfonyl chloride, 98% 4-三氟甲基苯磺酰氯 | 2991-42-6 | 247070 |
| 3-Fluorobenzaldehyde, 98% 3-氟苯甲醛 | 456-48-4 | 611928 |
| Benzotriazol-1-yloxytris(dimethylamino)-phosphonium hexafluorophosphate, 98%, for synthesis 苯并三唑-1-基氧基三(二甲氨基)鏻六氟磷酸盐 | 56602-33-6 | 536379 |
| 1-Fluoro-4-(methylsulfinyl)benzene, 99% 1-氟-4-(甲基亚磺酰基)苯 | 658-14-0 | 190255 |
| 4,4'-(Hexafluoroisopropylidene)diphthalic anhydride, 99% 4,4'-(六氟亚异丙基)邻苯二甲酸酐 | 1107-00-2 | 100605 |
| Tetrafluoroterephthalonitrile, 97% 四氟对苯二甲腈 | 1835-49-0 | 215523 |
| 4-Fluorophenol, 99%, for synthesis 4-氟苯酚 | 371-41-5 | 143496 |
| 4-(Trifluoromethyl)phenol, 98% 4-三氟甲基苯酚 | 402-45-9 | 127091 |
| 4-Fluorostyrene, 97%, stabilizer:0.1 % TBC 4-氟苯乙烯 | 405-99-2 | 568733 |
| 2,3,4,5,6-Pentafluorostyrene, 97%, stabilized with TBC 2,3,4,5,6-五氟苯乙烯 | 653-34-9 | 532259 |
| 1,2-Difluorobenzene, 98% 1,2-二氟苯 | 367-11-3 | 178917 危化品 |
| Fluorobenzene, 99%, for synthesis 氟苯 | 462-06-6 | 948533 危化品 |
| 1-Fluoronaphthalene, 99% 1-氟萘 | 321-38-0 | 985262 |
| 2-Nitro-4-(trifluoromethyl)benzenesulfonyl chloride, 95% 2-硝基-4-(三氟甲基)苯磺酰氯 | 837-95-6 | 965059 |
| Hexafluorobenzene, 98% 六氟苯 | 392-56-3 | 167329 |
| 1-Chloro-4-fluorobenzene, 98% 1-氯-4-氟苯 | 352-33-0 | 177723 危化品 |
| 2-Aminobenzotrifluoride, 99% 2-三氟甲基苯胺 | 88-17-5 | 145017 危化品 |
| 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane, 98% 2,2-双(3-氨基-4-羟基苯基)六氟丙烷 | 83558-87-6 | 488260 |
| Bromopentafluorobenzene, 99% 溴五氟苯 | 344-04-7 | 215712 |
| 2,3,4,5,6-Pentafluorobenzoic acid, 99% 2,3,4,5,6-五氟苯甲酸 | 602-94-8 | 316165 |
| 4-Iodobenzotrifluoride, 98% 4-碘代三氟甲苯 | 455-13-0 | 330887 |
| 3-(Trifluoromethyl)benzaldehyde, 98% 3-三氟甲基苯甲醛 | 454-89-7 | 515659 |
| 2,3,4,5-Tetrafluorobenzoic acid, 98% 2,3,4,5-四氟苯甲酸 | 1201-31-6 | 222946 |
| Iron(III) trifluoromethanesulfonate, 90% 三氟甲磺酸铁(III) | 63295-48-7 | 1443250 |
| N-Phenyl bis(trifluoromethanesulfon)imide, 98%, for synthesis N-苯基双(三氟甲基磺酰)亚胺 | 37595-74-7 | 949020 |
| 4-Bromobenzotrifluoride, 99%, for synthesis 4-溴三氟甲苯 | 402-43-7 | 982577 |
| 2-Fluoronitrobenzene, 99% 2-氟硝基苯 | 1493-27-2 | 245461 |
| 4-Fluorobenzoic acid, 99% 4-氟苯甲酸 | 456-22-4 | 223226 |
| 4-Fluorobenzonitrile, 99% 4-氟苯腈 | 1194-02-1 | 229389 |
| 9-Fluorenone, 99% 9-芴酮 | 486-25-9 | 366077 |
| 4-Chlorobenzotrifluoride, 98%, for synthesis 4-氯三氟甲苯 | 98-56-6 | 932999 危化品 |
| Poly(vinylidene fluoride), average MW ~ 534000 聚偏二氟乙烯 | 24937-79-9 | 377254新 |
| Pentafluorobenzene, 99% 五氟苯 | 363-72-4 | 446634 |
| 2,2,2-trifluoro-n-phenylacetimidoyl chloride, 98% 2,2,2-三氟-N-苯基亚氨代乙酰氯 | 61881-19-4 | 934540新 |
| 3,5-Bis(trifluoromethyl)aniline, 98%, for synthesis 3,5-双(三氟甲基)苯胺 | 328-74-5 | 967822 |
| 1-Chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate), 96% 1-氯甲基-4-氟-1,4-二氮桥二环[2.2.2]辛烷二四氟硼酸盐 | 140681-55-6 | 980882 |
| 2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether, 97% 2-氯-1,1,2-三氟乙基二氟甲基醚 | 13838-16-9 | 440372 |
| Ammonium tetrafluoroborate, 99% 氟硼酸铵 | 13826-83-0 | 394191 |
| 1,1,1,3,3-Pentafluorobutane, 99% 1,1,1,3,3-五氟丁烷 | 406-58-6 | 254076 |
| 2,2,3,3,4,4,4-Heptafluorobutylamine, 97% 2,2,3,3,4,4,4-七氟丁基胺 | 374-99-2 | 116089 |
| Lithium hexafluorophosphate, 99.9% 六氟磷酸锂 | 21324-40-3 | 559730 |
溶剂：
| 品名 | CAS | 货号 |
|---|---|---|
| Methanol, 99.5%, for synthesis 甲醇 | 67-56-1 | 904020 危化品 |
| Ethanol, 99.7%, reagent grade, anhydrous 乙醇 | 64-17-5 | 983081 危化品 |
| Dichloromethane, 99.9%, SuperDry, with molecular sieves, water≤30 ppm, J&KSeal 二氯甲烷 | 75-09-2 | 908525促 危化品 |
| N,N-Dimethylformamide, 99.8%, SuperDry, with molecular sieves, Water≤50 ppm, J&KSeal N,N-二甲基甲酰胺 | 68-12-2 | 983353促 危化品 |
分析检测试剂：
| 品名 | CAS | 货号 |
|---|---|---|
| Methanol-d4, 99.8 atom%D 氘代甲醇-d4 | 811-98-3 | 114655促 |
| Chloroform-d, 99.8 atom%D, contains 0.03% v/v TMS 氘代氯仿 | 865-49-6 | 995425促 |
| Acetonitrile, 99.9%, HPLC/ACS 乙腈 | 75-05-8 | 134752 危化品 |
| Methanol, 99.9%, HPLC/ACS 甲醇 | 67-56-1 | 116481 危化品 |
| Ethanol-d6, anhydrous, 99 atom%D 氘代乙醇-d6 | 1516-08-1 | 349944 |
耗材：
| 品名 | CAS | 货号 |
|---|---|---|
| PTFE beaker, 400 ml 聚四氟乙烯烧杯 | / | 904764 |
| Plastic graduated cylinder, capacity: 250 ml 塑料量筒 | / | 963991 |
| Unheated magnetic stirrer, work plate material:Nylon+GF, max. stirring quantity[H2O]: 3L 不加热型磁力搅拌器 | / | 904605 |
智慧实验室：
| 品名 | CAS | 货号 |
|---|---|---|
| FindMolecule ELN, Academic Pro. ELN电子记录本系统服务 | / | 9269009 |
| FindMolecule IMS, Academic Pro. 实验室库存管理系统服务 | / | 9269005 |
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