细胞信号传导——细胞骨架信号通路相关产品精选
2025-10-20 · 产品方案 · 百灵威授权转载
细胞骨架在信号传导过程中具有重要作用,通过影响细胞的结构和细胞内的信号传导通路调节细胞; 细胞骨架信号通路是指通过调控细胞骨架系统(微管、微丝、中间纤维)的动态重组,介导细胞形态维持、运动迁移和胞内物质运输的分子网络。
该通路研究对理解生命基本过程具有关键意义。首先,上皮-间质转化过程中的细胞骨架重塑是胚胎发育和肿瘤转移的核心环节。其次,神经元轴突导向和突触形成依赖于微管和微丝的精确调控,其机制解析为神经发育疾病提供新见解。细胞骨架信号异常与多种疾病密切相关,包括肿瘤的发生发展,免疫细胞功能障碍,神经退行性疾病等。
百灵威提供细胞骨架信号通路中的小分子抑制剂和激动剂等活性化合物,助力信号通路研究。
靶点信息清晰明确,便于选择;
严格的质检,确保产品高纯度、高品质;
生物活性经多客户验证;
性价比高:每个产品可节约5%-20%成本。
小分子抑制剂、激动剂等活性化合物
| 品名 | CAS | 货号 |
|---|---|---|
| Paclitaxel, 99.5%, reagent, for R&D, stabilizes tubulin polymerization, resulting in arrest at the G2/M phase of the cell cycle and apoptotic cell death 紫杉醇 | 33069-62-4 | 932649 |
| Paclitaxel, 98%, reagent grade 紫杉醇 | 33069-62-4 | 985203 |
| CK-636, 98%, a cell permeable inhibitor of Arp2/3 complex CK-636 | 442632-72-6 | 1467042 |
| CW-069, 98%, an allosteric inhibitor of HSET CW-069 | 1594094-64-0 | 1831796 |
| Tanespimycin, 97%, a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90 坦螺旋霉素 | 75747-14-7 | 223054 |
| ELR510444, 98%, a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation ELR510444 | 1233948-35-0 | 2275949 |
| SC66, 98%, a novel Akt inhibitor SC66 | 871361-88-5 | 2276028 |
| FRAX597, 99%, a potent group I p21-activated Kinases (PAKs) inhibitor FRAX597 | 1286739-19-2 | 2286509 |
| Combretastatin A-4, 98%, a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM 康普瑞汀 | 117048-59-6 | 266725 |
蛋白免疫印迹(WB)
| 品名 | CAS | 货号 |
|---|---|---|
| Bovine serum albumin, 98%, Australia origin, low IgG, low fatty acid 牛血清白蛋白 | 9048-46-8 | 109636 |
| Acrylamide, 99% 丙烯酰胺 | 79-06-1 | 166974 危化品 |
| Super ECL Plus Detection Reagent (component A), used with 1912570 Super ECL Plus超敏发光液(A液) | / | 946079 |
| Super ECL Plus Detection Reagent (component B), used with 946079 Super ECL Plus超敏发光液(B液) | / | 1912570 |
| Sodium dodecyl sulfate, 99%, for biochemistry 十二烷基硫酸钠 | 151-21-3 | 105893促 |
核心生化试剂
| 品名 | CAS | 货号 |
|---|---|---|
| Premium Fetal Bovine Serum 精制胎牛血清 | / | 9410422 |
| 4-Nonylphenyl-polyethylene glycol 4-壬基苯基-聚乙二醇 | 9016-45-9 | 931454 危化品 |
| 2-Mercaptoethanol, 99%, for electrophoresis and molecular biology 2-巯基乙醇 | 60-24-2 | 249096促 危化品 |
| D-(+)-Glucose, 99%, for bio D-(+)-葡萄糖 | 50-99-7 | 936778促 |
| Proteinase K, for bio, 30-40U/mg 蛋白酶 K | 39450-01-6 | 968706 |
| Acrylamide, 99% 丙烯酰胺 | 79-06-1 | 166974 危化品 |
| Sodium dodecyl sulfate, 99%, for electrophoresis 十二烷基硫酸钠 | 151-21-3 | 160975促 |
相关耗材
| 品名 | CAS | 货号 |
|---|---|---|
| Single-channel mechanical pipettor, Volume range: 100 - 1000 μL, Increment: 5.0 μL 单道手动可调移液器 | / | 1122427 |
| Pipette tips, 1000 μL, blue, 1000 tips/pack 移液器吸头 | / | 672890 |
| 96-well UV-transparent microplate, Non-sterile, bagged, black without lid, 5 tips/bag, 10 bags/case 96孔紫外可透微孔板 | / | 9478529 |
| 96-well non-removable high-binding ELISA plate, Bagged, transparent without lid, 5 tips/bag, 20 bags/case 96孔不可拆高结合力酶标板 | / | 9478546 |
| Pipette tips, 10 μL, clear, low Retention, 1000 tips/pack 移液器吸头 | / | 1438538 |
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